Anti-Psychotics Explained and the History of Psychopharmacology (History of Psychiatric Drugs).

An overview of the history of psychiatric drugs and the development of typical and atypical antipsychotics.

Anti-psychotics explained, by reviewing the history of psychopharmacology, and the history of psychiatric drugs. 💡Anti-depressant Course: psycho.farm/antidepressant-course ================ Follow PsychoFarm: 🔴SUBSCRIBE ► youtube.com/c/Psychofarm?sub_confirmation=1 🧠Mental Health Resources: psycho.farm/services-4 ➡️Instagram: instagram.com/thepsychofarm/ ➡️Tiktok: tiktok.com/@thepsychofarm ➡️Twitter: twitter.com/ThePsychoFARM ================ Sources: Ramachandraiah CT, Subramaniam N, Tancer M. The story of antipsychotics: Past and present. Indian J Psychiatry. 2009;51(4):324-326. doi:10.4103/0019-5545.58304 Carpenter, W., Davis, J. Another view of the history of antipsychotic drug discovery and development. Mol Psychiatry 17, 1168–1173 (2012). doi.org/10.1038/mp.2012.121 The video delves into the history and development of antipsychotic medications, focusing on the differences between typical and atypical antipsychotics. It begins by exploring the psychoanalytic perspective on mental health disorders prevalent until the 1950s, highlighting the lack of effective treatments. This changed with the discovery of chlorpromazine (Thorazine) in the 1950s, marking a paradigm shift towards biological approaches to treating mental illness. Chlorpromazine's efficacy in treating schizophrenia led to a surge in its usage and the emergence of psychopharmacology as a field. However, typical antipsychotics like Thorazine had significant side effects, including extrapyramidal symptoms (EPS). The introduction of haloperidol (Haldol) in 1958 offered a more potent alternative with fewer side effects. The classification of antipsychotics into high, middle, and low potency helped guide treatment choices based on their receptor affinities. The video also touches on the serendipitous discoveries of antidepressants like MAOIs and TCAs, shedding light on the evolution of psychiatric medication. The term "atypical antipsychotics" emerged with the discovery of clozapine, marking a new generation of medications. Overall, the video provides a comprehensive overview of the development of antipsychotics, from their serendipitous discoveries to their classification and evolving understanding of mental illness. ================ #psychopharmacology #pharmacology #pmhnp #psychnp 00:00 Farm-House Intro 00:31 Intro 00:50 Can't Not Talk About Freud 01:34 Pre-1950 Psych Treatment 02:08 Thorazine 02:47 Mood Stabilizer Tangent 05:25 Dopaminergic Pathways 07:55 Haldol 08:51 Potent Potables 10:22 Anti-Depressant Tangent