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How The Immune System ACTUALLY Works – IMMUNE

Kurzgesagt – In a Nutshell

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  • Recommended by 3 people, in Hacker News, across 3 different months.
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For anyone, no background needed. Education, not medical advice.

26M views5 years ago3 recommendations

Immunity and infectionThe immune systemInfectious diseaseCancer biology

Kurzgesagt explains the complex network of cells and organs that make up the human immune system.

To preorder IMMUNE click here: kgs.link/ImmuneBook –– It’s available in English and German and at online retailers it should be available in pretty much all countries too. Sources & further reading: sites.google.com/view/sources-immunesystemexplained/ The human immune system is the most complex biological system we know, after the human brain, and yet, most of us never learn how it works. Or what it is. Your immune System consists of hundreds of tiny and two large organs, it has its own transport network spread throughout your body. Every day it makes hundreds of billions of fresh cells. It is not some sort of abstract entity. Your immune system is YOU. Your biology protecting you from the billions of microorganisms that want to consume you and from your own perverted cells that turn into cancer. It's so manifold that it is impossible to cover in one video, so we’ll make a series looking at different aspects of it. Today, what happens when your body is invaded and your first lines of defenses are engaged in a fight for life and death? OUR CHANNELS ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ German Channel: kgs.link/youtubeDE Spanish Channel: kgs.link/youtubeES HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ This is how we make our living and it would be a pleasure if you support us! Get Merch designed with ❤ kgs.link/shop-147 Join the Patreon Bird Army 🐧 kgs.link/patreon DISCUSSIONS & SOCIAL MEDIA ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Reddit: kgs.link/reddit Instagram: kgs.link/instagram Twitter: kgs.link/twitter Facebook: kgs.link/facebook Discord: kgs.link/discord Newsletter: kgs.link/newsletter OUR VOICE ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ The Kurzgesagt voice is from Steve Taylor: kgs.link/youtube-voice OUR MUSIC ♬♪ ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ 700+ minutes of Kurzgesagt Soundtracks by Epic Mountain: Spotify: kgs.link/music-spotify Soundcloud: kgs.link/music-soundcloud Bandcamp: kgs.link/music-bandcamp Youtube: kgs.link/music-youtube Facebook: kgs.link/music-facebook The Soundtrack of this video: Emergence Soundcloud: bit.ly/3jEvquO Bandcamp: bit.ly/2X30D2X Life Soundcloud: bit.ly/3CBAybK Bandcamp: bit.ly/37xr4ju If you want to help us caption this video, please send subtitles to subtitle@kurzgesagt.org You can find info on what subtitle files work on YouTube here: support.google.com/youtube/answer/2734698?hl=en-GB&ref_topic… Thank you! 🐦🐧🐤 PATREON BIRD ARMY 🐤🐧🐦 ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Many Thanks to our wonderful Patreons (from kgs.link/patreon) who support us every month and made this video possible: BBumbrazz, Sir Harry Farr, Abigail von Kelsch, Szabolcs Dombi, Conner Wilson, Enoch, Moody Bastard, Diego Marcheselli, Paxton LaRiviere, Richard Hagen, Robin Harn, Izzy Cro

Why it's here

3 people recommend this

What people say. Recommended as an exceptionally clear and beautifully animated explanation of the human immune system.

RealFloridaManin Hacker News • Recommends

On “Immunity from Covid-19 Infection May Be as Strong as from Vaccination”

…ll always target the ACE2 binding site. The spike protein can mutate to bind to it differently, but it will always require a spike protein. (Biology is Analog, not digital) Thus targeting the spike protein is more efficient as it will be highly conserved. There is a video series that does a nice job of breaking down how your immune response works: link to this video The vaccine is more effective at developing anti-bodies for the spike protein as it is the only protein exposed during the process. An analogy that has helped some of my family: The virus is like a missile, and your immune system is a anti-missile system. Regardless of what the missile looks like, it has to have a warhead, and that warhead…
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chasilin Hacker News • Recommends

On “T Cells Can Activate Themselves to Fight Tumors”

There is nothing in the behavior of cells that is reflective of human intelligence. Cells are "amino acid robots." They string the 26 programmed amino acids into exotic plastics/proteins to execute their programmed functions. There is no relation to human behavior in cellular behavior. At the end of an infection, most immune cells trigger "apoptosis" (controlled cellular "suicide"). At the end of a riot, police obviously do not do this. You might find this Kurzgesagt introduction to immune system behavior interesting. There are several videos in this sequence, and Kurzgesagt ultimately published a book that is worth reading. link to this video
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pixl97in Hacker News • Recommends

On “Chronic fatigue syndrome may have a post-viral infection origin”

> is there a department of immunology that takes over or even contributes. Because we don't see the immune system as the organ it is. Which is odd that things like vaccines are effectively medicines for that organ. But at the end of the day we still don't know 'that much' about the immune system because of its extreme complexity. It's still very difficult or impossible to target a bad acting immune response in an individual without disabling all the immune system (and yea, this puts you at a lot of risk). I like the series that Kurzgesagt made on the immune system as a way to explain this complexity a little more simply. link to this video
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chasilin Hacker News • Mentions

On “Toxoplasma Gondii significantly alters wolf behavior”

The question is how your medication interacts with "somatic hypermutation" which enables your dendritic cells to launch the cascade via t-cells which triggers antibody production by your b-cells. It would be useful to understand how your medication interacts with this process. link to this video Somatic hypermutation has a small discussion in the Kerzegast book. I understand that somatic hypermutation, by the removal of uracil, plays two roles, first in initial recognition of a pathogen, then second in tuning the response for variants. As I understand it, this only happens in germinal centers, the lymph nodes. link This is a question for an infectious disease specialist.
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