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Coronavirus Update 98: Rapid COVID 19 Antigen Testing at Home - A Possible Breakthrough

MedCram - Medical Lectures Explained CLEARLY

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  • Recommended by 2 people, in Hacker News, across 2 different months.
  • Presented by Roger Seheult, MD, as the video describes them
  • The description links 3 papers.
  • May be out of date. Findings or guidance it presents have likely moved on.

Assumes interest and some biology. Education, not medical advice.

205K views6 years ago2 recommendations

Immunity and infectionClinical medicineInfectious diseaseDiagnosis and clinical reasoningPublic health and policy

Roger Seheult, MD discusses the potential of cheap, frequent, at-home rapid antigen tests to curb the spread of COVID-19.

Professor Roger Seheult, MD discusses the current COVID-19 testing strategy in the United States that the CDC estimates picks up less than 10% of infections. Dr. Seheult of MedCram.com features snippets from a recent This Week in Virology (Episode 640) with Dr. Michael Mina of Harvard who explains that the technology exists for at home, inexpensive, self-administered, "paper" COVID-19 antigen tests that are likely accurate enough to pick up the vast majority of infectious cases of COVID-19. And how lower sensitivity of inexpensive tests may be ideal for a screening test that is performed with high frequency. Utilization of these "daily quick tests" may provide the optimal path forward to curtail the growth of COVID-19 and open schools and our economy in a much safer way. (This video was recorded July 20, 2020). LINKS / REFERENCES: See a MedCram Q/A follow up to this video with Dr. Michael Mina: youtu.be/cP-MHKU_cQE Dr. Mina speaks more about COVID-19 testing responds to questions from the comment section below. This Week in Virology Episode 640 | youtube.com/watch?v=kDj4Zyq3yOA NEJM | nejm.org/doi/pdf/10.1056/NEJMc2001737 NYU Study on Abbott ID Now | biorxiv.org/content/10.1101/2020.05.11.089896v1.full.pdf New York Times | nytimes.com/2020/07/03/opinion/coronavirus-tests.html Test Sensitivity is Secondary to Frequency (Dr. Mina) | medrxiv.org/content/10.1101/2020.06.22.20136309v2 Abbott ID Now | abbott.com/corpnewsroom/product-and-innovation/how-id-now-ta… CNN Test Costs | cnn.com/2020/07/15/health/coronavirus-test-cost/index.html Johns Hopkins Tracker | coronavirus.jhu.edu/map.html Live Science | livescience.com/coronavirus-should-schools-reopen-fall.html Korean CDC | cdc.go.kr/board/board.es?mid=a30402000000&bid=0030 Washington Post | washingtonpost.com/health/long-delays-in-getting-test-result… Reuters | reuters.com/article/us-questdiagnostics-outlook/quest-says-m… THE MEDCRAM WEBSITE: Visit us for videos on over 60 medical topics and CME / CEs for medical professionals: medcram.com SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL: youtube.com/user/MEDCRAMvideos?sub_confirmation=1 Get notified of new videos by hitting the bell icon: PREVIOUS COVID-19 UPDATES: Please visit MedCram.com for the full series: - Coronavirus Pandemic Update 97: Vitamin D & COVID-19 Immunity, The Endothelium, & Deficiencies youtu.be/Mdc7T2UTHBI - Coronavirus Pandemic Update 96: RNA Vaccine; Ivermectin; von Willebrand Factor and COVID-19 youtu.be/kk7KNBak-i0 - Coronavirus Pandemic Update 95: Widespread Clotting on Autopsy; New COVID-19 Prognostic Data youtu.be/bPDVzt79UMU - Coronavirus Pandemic

Why it's here

2 people recommend this

What people say. Recommended for its clear explanation of how rapid antigen testing works as a public health screening tool.

jdcin Hacker News • Recommends

On “Interview with Bill Gates on Covid, social media”

Right - see the MedCram lectures on the topic: How to Beat COVID-19 with At-Home, Rapid Result Testing: 5 Min. Summary by Dr. Mina (Antigen Tests) link Coronavirus Pandemic Update 98: At Home COVID-19 Testing - A Possible Breakthrough (~ 15 min) link to this video At Home, Cheap, COVID-19 Tests with Results in 15 Minutes: How to Fix Testing with Dr. Michael Mina (~ 1 hr) link
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devyin Hacker News • Recommends

On “U.S. to require negative Covid-19 tests for international air passengers”

…ve COVID. And the public health measures of testing / contact tracing ONLY works if testing results come back quick. PCR tests are neither fast nor cheap, so those are not as effective in prevention of spreading because you don't do those all the time (slow + expensive). Medcram has a good video talking about this. 3 1: link 2: link 3: link to this video…
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acqqin Hacker News • Mentions

On “Saliva based Covid test: results in 45 minutes”

The visual explanation of the ideas and concepts presented there, also mentioned in the later podcast: Medcram: “Coronavirus Pandemic Update 98: At Home COVID-19 Testing - A Possible Breakthrough” link to this video Also, regarding the Ct value, from: “Interpreting the COVID-19 Test Results: a Guide for Physiatrists” link In PCR tests “the diagnosis is made based on the threshold cycle (Ct) value. Ct is defined as the cycle number when the sample fluorescence exceeds a chosen threshold above the calculated background fluorescence.5 In other words, the lower the Ct value of a specific gene, the more the gene exists in the sample. However, the problem with a Ct-based diagnosis is that there is no absol…
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