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The Link Between Proteins, Alzheimer’s and Parkinson’s Diseases

University of California Television (UCTV)

1.4M subscribers • 35 videos on Rounds • Health institution

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  • Published by University of California Television (UCTV), one of the health institutions Rounds lists. Nobody has recommended it in the communities yet, so it ranks below community picks.
  • Presented by Joan-Emma Shea, professor at UC Santa Barbara, as the video describes them

Assumes interest and some biology. Education, not medical advice.

99K views2 years ago

Brain and nervesClinical medicineDementia and Alzheimer'sNeurological conditionsCells and molecules

Joan-Emma Shea explains how the tau protein can self-assemble into toxic aggregates, driving neurodegenerative diseases like Alzheimer's and Parkinson's.

Proteins are large biomolecules that play critical roles in a host of cellular processes, from cell signaling to regulating the immune system. However, these life-giving proteins can form toxic aggregate species that have been linked to several neurodegenerative diseases, including Alzheimer’s Disease and Parkinson’s Disease. In this program, UC Santa Barbara professor Joan-Emma Shea discusses the tau protein as a model system to study neurodegeneration. Shea says this protein plays a functional role in stabilizing microtubules in brain cells, but it can also self-assemble to form amyloid fibrils (large “clumps” of Tau proteins). There are several neurodegenerative diseases linked to tau assembly, including Alzheimer’s Disease, Pick’s Disease, and chronic traumatic encephalopathy, and they are collectively known as tauopathies. Shea discusses new insights into tauopathies and targets for therapeutics. Recorded on 06/26/2024. [10/2024] [Show ID: 40083] Donate to UCTV to support informative & inspiring programming: uctv.tv/donate More videos from: GRIT Talks (uctv.tv/grit) Explore More Science & Technology on UCTV (uctv.tv/science) Science and technology continue to change our lives. University of California scientists are tackling the important questions like climate change, evolution, oceanography, neuroscience and the potential of stem cells. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (uctv.tv)

Why it's here

From a health institution

University of California Television (UCTV) is on Rounds' list of health institutions, and this upload is one of its most-watched lectures or explainers. Nobody has recommended it in the communities yet, so it ranks below community picks.