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Epigenetics and Aging: The effects of DNA breakage and repair
Harvard Medical School
338K subscribers • 24 videos on Rounds • Health institution
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Assumes interest and some biology. Education, not medical advice.
160K views3 years ago
Aging and longevityHow the body worksBiology of agingGenetics and genomicsCells and molecules
How the loss of epigenetic information drives aging in mice and how restoring it can reverse age-related symptoms.
A 13-year international study in mice demonstrates that loss of epigenetic information, which influences how DNA is organized and regulated, can drive aging independently of changes to the genetic code itself. It also shows that restoring the integrity of the epigenome reverses age-related symptoms. Version that includes an audio-description: youtu.be/MYtaqgGZv8I Learn more at hms.harvard.edu/news/loss-epigenetic-information-can-drive-a…Why it's here
From a health institutionHarvard Medical School is on Rounds' list of health institutions, and this upload is one of its most-watched lectures or explainers. Nobody has recommended it in the communities yet, so it ranks below community picks.