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Electron transport chain

Harvard Online

257K subscribers • 3 videos on Rounds

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  • Recommended by 6 people, in Hacker News, across 5 different months.
  • Presented by Rob Lue, Professor at Harvard University, as the video describes them

Assumes interest and some biology. Education, not medical advice.

3.6M views9 years ago6 recommendations

How the body worksCells and moleculesPhysiology

Rob Lue explains how the mitochondrial electron transport chain works to produce ATP and the implications of mitochondrial diseases.

From our free online course, “Cell Biology: Mitochondria”: edx.org/course/cell-biology-mitochondria-harvardx-mcb64-1x-1… Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance. — Subscribe to our channel: youtube.com/channel/UCKJyv_uNh3LhYFKmwaB63bA?sub_confirmatio… — Sign up for emails about new courses: harvardx.link/email — HarvardX courses on edX: edx.org/school/harvardx — Harvard University's online courses: online-learning.harvard.edu/ HarvardX empowers the faculty of Harvard University to create high-quality online courses in subjects ranging from computer science to history, education, and religion.

Why it's here

6 people recommend this

What people say. Highly recommended as a clear, mind-blowing animation of molecular machines and cellular respiration.

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'Molecular machines' is not an overstatement. Here's an example of some of them working in harmony to maintain an essential electrochemical gradient across the lipid bilayer that encapsulates the mitochondria: link to this video It's a 7 minute video, if you only have a little time, skip around, but make sure you listen to the part starting at 6:17. DNA isn't just the blueprint for the machine or the blueprint for the factory that makes the machine, it's the blueprint for the entire supply chain required to build and operate an entire chemical industry of mind-bending complexity. Like doubling grains of rice on each square of a checkerboard, if you wanted to create a complete catalog of all possible co…

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On “I should have loved biology”

The thing that drove this home for me were the biovisions animations which got me to go back and basically learn high school biology. Seeing the mechanical nature of gene transciption and chemical signaling blew my mind. link link to this video On the other hand, I don't buy his thing about wishing his high school teacher had presented it differently. No on else can make you interested in this stuff. The best they can do is provide resources like the ones above.

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It's a very complex topic (especially if you aren't a chemist). I can't find an accessible video on the topic, but you want to look up photosystem II repair. You need to search up D1 replacement in photosystem II. To get a flavour of the nanomachine aspect of it all, check out this video on electron transport across membranes ( link to this video ). Electron transport in proteins is crazy complex and actually amounts to molecular circuits where energy is guided to different spots inside proteins complexes in a unidirectional fashion. This guy is the grand daddy of the field ( link ).

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