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David Sinclair | Why We Age and Why We Don't Have To | Talks at Google

Talks at Google

2.4M subscribers • 10 videos on Rounds

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  • Recommended by 2 people, in Hacker News, across 2 different months.
  • Presented by David Sinclair, professor of genetics at Harvard Medical School, as the video describes them
  • Sells products. The upload promotes a product, supplement, program or service, or the speaker sells what they recommend.
  • Debated among experts. Its central claim is contested, so look for the other side.

For anyone, no background needed. Education, not medical advice.

2.2M views7 years ago2 recommendations

Aging and longevityBiology of agingLongevity interventionsHealthspan and aging well

David Sinclair explains the biological processes of aging and discusses lifestyle interventions and scientific breakthroughs that could slow or reverse it.

David Sinclair, professor of genetics at Harvard Medical School, discusses his new book "Lifespan", which distills his cutting-edge research findings on the biological processes underpinning aging. Sinclair describes lifestyle hacks we can undertake now to combat aging, as well as future scientific breakthroughs that promise to slow down—and even reverse—the aging process. Moderated by: Sam Phippen Get the book: goo.gle/2LXCd2P

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2 people recommend this

What people say. Recommended as an engaging introduction to the science of aging and longevity interventions.

LinuxBenderin Hacker News • Recommends

On “Scientist David Sinclair on why we age and why he thinks we don’t have to (2019)”

This is not a great article. It leaves out Dr. Sinclairs work, further developing discoveries by Dr. Yamanaka specifically around the four transcription factors (Oct3/4, Sox2, Klf4, and c-myc), turning any cells back into pluripotent stem cells. More important, leaving c-myc disabled, the cell reverts to a younger age. This is what Dr. Sinclair has been working on recently, to completely reverse macular degeneration. He has been able to regrow damaged optic nerves all the way from the eye back to the brain. Here is a talk he did at Google 1 He briefly talks about the ethics of this here 2. 1 - link to this video 2 - link
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DrRobinsonin Hacker News • Recommends

On “Ask HN: What are you surprised isn’t being worked on more?”

Seems like many people are new to this concept and feel skeptical so here are some useful resources: * Kurzgesagt: How to Cure Aging – During Your Lifetime? (7:20) link * Kurzgesagt: Why Age? Should We End Aging Forever? (6:48) link * Why we should cure ageing (11:30) - Heads up, it's a book intro link * Ageless: The New Science of Getting Older Without Getting Old (Book, not yet released in the US) link * Lifespan: Why we age and why we don't have to (book) link * Google talk: Why We Age and Why We Don't Have To (55:13) - By the author of the book link to this video Edit: * If you wish to contribute to this kind of research make sure to check out SENS: link
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fossuserin Hacker News • Mentions

On “Monday was my 46th birthday and likely my last (2013)”

…ve to die, just like there was no reason for all the deaths in child birth in early human history. It's a failure of our current capabilities. I don't know if any of the claims in Lifespan 1 hold up, but if they do stopping aging may be easier than people previously thought. Either way - I'm hoping we figure it out sooner rather than later. 1: link to this video…
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